Origin of 21+2_1^+ Excitation Energy Dependence on Valence Nucleon Numbers

It has been shown recently that a simple formula in terms of the valence nucleon numbers and the mass number can describe the essential trends of excitation energies of the first $2^+$ states in even-even nuclei. By evaluating the first order energy shift due to the zero-range residual interaction, we find that the factor which reflects the effective particle number participating in the interaction from the Fermi orbit governs the main dependence of the first $2^+$ excitation energy on the valence nucleon numbers.Comment: 9 pages, 5 figure

Evolution of breast cancer therapeutics: Breast tumour kinase’s role in breast cancer and hope for breast tumour kinase targeted therapy

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). © 2014 Baishideng Publishing Group Inc.There have been significant improvements in the detection and treatment of breast cancer in recent decades. However, there is still a need to develop more effective therapeutic techniques that are patient specific with reduced toxicity leading to further increases in patients’ overall survival; the ongoing progress in understanding recurrence, resistant and spread also needs to be maintained. Better understanding of breast cancer pathology, molecular biology and progression as well as identification of some of the underlying factors involved in breast cancer tumourgenesis and metastasis has led to the identification of novel therapeutic targets. Over a number of years interest has risen in breast tumour kinase (Brk) also known as protein tyrosine kinase 6; the research field has grown and Brk has been described as a desirable therapeutic target in relation to tyrosine kinase inhibition as well as disruption of its kinase independent activity. This review will outline the current “state of play” with respect to targeted therapy for breast cancer, as well as discussing Brk’s role in the processes underlying tumour development and metastasis and its potential as a therapeutic target in breast cancer

The A&A Experience With Impact Factors

There is a widespread impression that the scientific journal "Astronomy & Astrophysics" (A&A) has a smaller impact, as measured by citations to articles, than some of the other major astronomy journals. This impression was apparently supported - and probably created - by the Journal Citation Report (JCR), which is prepared annually by the Institute of Scientific Information (ISI) Web of Knowledge. The published poor impact factor of A&A was in fact wrong and was due to a serious flaw in the method used by ISI Web of Knowledge to determine it. The resulting damage inflicted upon A&A by the JCR is incalculable.Comment: 4 pages, to be published in A. Heck (ed.) "Organizations and Strategies in Astronomy, Vol. 5" (Kluwer, 2004

Diffusion in a continuum model of self-propelled particles with alignment interaction

In this paper, we provide the $O(\epsilon)$ corrections to the hydrodynamic model derived by Degond and Motsch from a kinetic version of the model by Vicsek & coauthors describing flocking biological agents. The parameter $\epsilon$ stands for the ratio of the microscopic to the macroscopic scales. The $O(\epsilon)$ corrected model involves diffusion terms in both the mass and velocity equations as well as terms which are quadratic functions of the first order derivatives of the density and velocity. The derivation method is based on the standard Chapman-Enskog theory, but is significantly more complex than usual due to both the non-isotropy of the fluid and the lack of momentum conservation